Low dose Ketamine is meant primarily for the treatment of refractory depression, depression and pain related to palliative care, and chronic refractory neuropathic pain.
Contraindications include: Age < 18 years, unstable medical conditions including hypertension, angina, severe respiratory illness, glaucoma, schizophrenia, psychosis, or anything that would be considered a risk for outpatient procedures. Chronic use of high doses of benzodiazepines may also impact the response to ketamine.